health (Business Opportunities - Marketing & Sales)
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Item ID 9465105 in Category: Business Opportunities - Marketing & Sales
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health researchers conducted an observational, ecological study to evaluate the impact of the COVID-19 pandemic on antibiotic prescribing in the United States between February and December 2020. The total number of antibiotic prescriptions dropped by 26 percent compared to the same period in the previous 3 years, with the most significant decline being prescriptions in children. While COVID-19 prevention measures such as facemasks and school closures were associated with lower prescribing among children, there was a positive correlation between COVID-19 cases and antibiotic prescribing in adults, implicating behavioral norms as drivers of prescribing practices. Resistance to colistin, an antibiotic often viewed as a last-resort therapy against multi-drug-resistant Gram-negative bacteria (GNB), has emerged in Enterobacteriaceae species. OHT and collaborators analyzed the impact of regulatory policies on colistin use on the prevalence of resistant E. coli using a One Health approach. Since the discovery of mcr-1, a plasmid-mediated colistin resistance gene, regulations and policies have been created to maintain some of colistin’s efficacy. These measures have resulted in a steep decline in colistin production and the prevalence of colistin-resistant E. coli between 2016 and 2019 A study co-authored by OHT’s Ramanan Laxminarayan and Eili Klein shows that discontinuing antibiotics early (three to four days after initiation) was not associated with higher mortality in a large cohort of US patients hospitalized with suspected culture-negative serious infection (CNSI). Early discontinuation was also not linked to greater odds of hospital discharge to hospice care than patients receiving a full five-day course. Together with other studies on post-discharge health outcomes following early antibiotic discontinuation, these findings can help promote antibiotic stewardship and best practices among medical professionals. | |
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| Target Nation: All Nations Target City : UNITED STATES Last Update : 01 February 2024 1:15 PM Number of Views: 131 | Item Owner : hadaniw Hidmarkcom Contact Email: Contact Phone: 380956450x041 |
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2024-11-18 (0.223 sec)